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Skin cancer screening: what doctors look for and when to get a skin check

Guides 6 min read
Guides·Sara NassereddinHealth Technology Writer·July 25, 2026· 6 min read

Melanoma is one of the most dangerous cancers — and one of the most preventable when caught early. Here's what a skin check involves, what warning signs to look for, and how often you should be screened.

The ABCDE rule for suspicious moles

The ABCDE criteria are a clinical and self-examination tool for identifying features associated with melanoma. Any mole or pigmented lesion that matches one or more of these should be seen by a doctor promptly.

Other types to know

  • Basal cell carcinoma (BCC) — pearly or waxy bump, often with a rolled border; may have a central depression or ulcer; common on sun-exposed areas; rarely spreads
  • Squamous cell carcinoma (SCC) — firm red nodule or rough scaly lesion; can ulcerate; more likely than BCC to spread if untreated
  • Actinic keratosis — a pre-cancerous rough scaly patch on sun-exposed skin; can progress to SCC if left untreated

What happens at a skin check

A dermatologist performs a full-body skin examination, typically using a dermatoscope — a handheld illuminated magnifier that reveals subsurface features not visible to the naked eye. Any suspicious lesion is photographed and mapped. A biopsy (punch biopsy or excision) is taken from lesions that cannot be confidently categorised as benign.

Total-body photography — baseline photos of all moles — is used in high-risk patients to detect change over time. Digital dermoscopy systems allow precise comparison of individual lesions at each visit.

Who should screen and how often

Annual full-body skin checks are recommended for: people with a personal or close family history of melanoma; those with many moles (> 50), atypical moles or moles present since childhood; fair-skinned individuals with significant sun exposure history; people who have had repeated sunburns, particularly blistering burns in childhood; and immunosuppressed individuals.

For average-risk adults, self-examination monthly and a dermatology review every 2–3 years is a reasonable baseline. Those in high-UV environments or with extensive occupational sun exposure should check more frequently.